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Furosemide sodium
CAS No. 41733-55-5
Furosemide sodium ( —— )
产品货号. M34751 CAS No. 41733-55-5
Furosemide sodium 是 Na+/K+/2Cl-?(NKCC)，NKCC1 和 NKCC2 共转运蛋白的有效的和具有口服活性抑制剂。Furosemide sodium 也是 GABAA 受体拮抗剂，对含 α6 受体的选择性是含 α1 受体的 100 倍。Furosemide sodium 用作利尿试剂，用于充血性心力衰竭，高血压和水肿的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ￥227 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Furosemide sodium
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Furosemide sodium 是 Na+/K+/2Cl-?(NKCC)，NKCC1 和 NKCC2 共转运蛋白的有效的和具有口服活性抑制剂。Furosemide sodium 也是 GABAA 受体拮抗剂，对含 α6 受体的选择性是含 α1 受体的 100 倍。Furosemide sodium 用作利尿试剂，用于充血性心力衰竭，高血压和水肿的研究。
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产品描述Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl-?(NKCC) cotransporter, NKCC1 and NKCC2.?Furosemide sodium is also a GABAA?receptors antagonist and displays 100-fold selectivity for?α6-containing receptors than?α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体GABA Receptor | Na-K-Cl cotransporter
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研究领域——
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适应症——
化学信息
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CAS Number41733-55-5
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分子量352.73
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分子式C12H10ClN2NaO5S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : ≥ 150 mg/mL (425.25 mM) H2O 中的溶解度 : 100 mg/mL (283.50 mM; 超声助溶)
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SMILESO=C([O-])C1=CC(S(=O)(N)=O)=C(Cl)C=C1NCC2=CC=CO2.[Na+]
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. C M Gillen, et al. Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family. J Biol Chem. 1996 Jul 5;271(27):16237-44.?
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